beta- and gamma-Lumicolchicine

March 02, 2018

Colchicine is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (Colchicum autumnale, also known as autumn crocus, meadow saffron or naked ladies).

Colchicine is a medication most commonly used to treat gout. In addition to gout, it is used to treat familial Mediterranean fever, pericarditis, and Behçet’s disease.

The use of colchicine as a drug in food-producing animals is prohibited in the European Union.

Alpha, beta, and gamma-lumicholchicine are photochemical degradation products from colchicine. These metabolites lack many of the physiological actions of the parent colchicine. For this reason they are used as experimental control for colchicine actions.

ASCA GmbH has successfully synthesized beta- and gamma-Lumicolchicine (also known as Colchicine Impurity C, Colchicine Impurity G) and can offer these photoisomers with chemical purity >98%.

 

beta-Lumicolchicine
gamma-Lumicolchicine
Synonyme: Impurity C
CAS-No. 6901-13-9
Synonyme: Impurity G
CAS-No. 6901-14-0
 

 

 

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