VII β-Lactones

  1. C. Wedler, B. Costisella, H. Schick,
    Synthesis of Enantiomerically Pure β-Lactones by the Tandem Aldol-Lactonization – A Highly Efficient Access to (3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one, the Key Intermediate for the Enzyme Inhibitors Tetrahydrolipstatin and Tetrahydroesterastin,
    J. Org. Chem. 1999, 64, 5301-5303.

  3. C. Wedler, H. Schick,
    Syntheses of β-Lactones, 7.
    Synthesis of β-Lactones by Aldolization of Ketones with Phenyl Ester Enolates: 3,3-Dimethyl-1-oxaspiro[3.5]nonan-2-one,

    Organic Synthesis 1997, 75, 116-122.

  5. C. Wedler, K. Kleiner, E. Gründemann, H. Schick,
    α-Chloro- and α,α-Dichloro-β-lactones by Aldolization of Carbonyl Compounds with Lithium Ester Enolates Derived from Chlorinated Phenyl Alkanoates – An Unusual Course of the Darzens Reaction,
    J. Chem. Soc., Perkin Trans. 1 1997, 1963-1967.

  7. C. Wedler, R. Ludwig, H. Schick,
    Application of enolates of activated carboxylic acid derivatives in organic synthesis – Novel syntheses of β-lactones,
    Pure Appl. Chem. 1997, 69, 605-608.

  9. C. Wedler, K. Kleiner, A. Kunath, H. Schick,
    Syntheses of β-Lactones , 6.
    One-step Synthesis of β-Lactones by Aldolization of Ketones or Aldehydes with 1-Acylbenzotriazoles,

    Liebigs Ann. Chem. 1996, 881-885.

  11. C. Wedler, A. Kunath, H. Schick,
    Unerwarteter Verlauf der Darzens-Reaktion von α-Chlorcarbonsäurephenylestern mit Carbonylverbindungen – Eine neuartige einstufige Synthese von α-Chlor-β-lactonen,
    Angew. Chem. 1995, 107, 2201-2202; Angew. Chem. Int. Ed. Engl. 1995, 34, 2028-2029.

  13. C. Wedler, A. Kunath, H. Schick,
    Synthesis of β-Lactones via Spontaneous Intramolecular Cyclization of O-Lithiated Phenyl β-Hydroxyalkanoates Obtained by the Aldolization of Ketones or Aldehydes with Lithium Enolates of Phenyl Esters,
    J. Org. Chem. 1995, 60, 758-760.