Publications

1. C. Wedler, B. Costisella, H. Schick,
   Synthesis of Enantiomerically Pure β-Lactones by the Tandem Aldol-Lactonization – A Highly Efficient Access to (3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one, the Key Intermediate for the Enzyme Inhibitors Tetrahydrolipstatin and Tetrahydroesterastin,
   J. Org. Chem. 1999, 64, 5301-5303.

 

2. C. Wedler, H. Schick,
   Syntheses of β-Lactones, 7.
   Synthesis of β-Lactones by Aldolization of Ketones with Phenyl Ester Enolates: 3,3-Dimethyl-1-oxaspiro[3.5]nonan-2-one,
   Organic Synthesis 1997, 75, 116-122.

 

3. C. Wedler, K. Kleiner, E. Gründemann, H. Schick,
   α-Chloro- and α,α-Dichloro-β-lactones by Aldolization of Carbonyl Compounds with Lithium Ester Enolates Derived from Chlorinated Phenyl Alkanoates – An Unusual Course of the Darzens Reaction,
   J. Chem. Soc., Perkin Trans. 1 1997, 1963-1967.

 

4. C. Wedler, R. Ludwig, H. Schick,
   Application of enolates of activated carboxylic acid derivatives in organic synthesis – Novel syntheses of β-lactones,
   Pure Appl. Chem. 1997, 69, 605-608.

 

5. C. Wedler, K. Kleiner, A. Kunath, H. Schick,
   Syntheses of β-Lactones , 6.
   One-step Synthesis of β-Lactones by Aldolization of Ketones or Aldehydes with 1-Acylbenzotriazoles,
   Liebigs Ann. Chem. 1996, 881-885.

 

6. C. Wedler, A. Kunath, H. Schick,
   Unerwarteter Verlauf der Darzens-Reaktion von α-Chlorcarbonsäurephenylestern mit Carbonylverbindungen – Eine neuartige einstufige Synthese von α-Chlor-β-lactonen,
   Angew. Chem. 1995, 107, 2201-2202; Angew. Chem. Int. Ed. Engl. 1995, 34, 2028-2029.

 

7. C. Wedler, A. Kunath, H. Schick,
   Synthesis of β-Lactones via Spontaneous Intramolecular Cyclization of O-Lithiated Phenyl β-Hydroxyalkanoates Obtained by the Aldolization of Ketones or Aldehydes with Lithium Enolates of Phenyl Esters,
   J. Org. Chem. 1995, 60, 758-760.